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Messed-up metabolism during development may lead guts to coil the wrong way

Experiments in tadpoles may provide clues to a condition in people called intestinal malrotation

Inside the African clawed frog, intestines grow just like humans': neatly coiled counterclockwise. Experiments now show how that process can go awry.

Interfering with tadpoles' metabolism leads to a chain of cellular disruptions that causes their intestines to grow in the wrong direction, researchers from North Carolina State University in Raleigh report February 19 in Development.


This article was downloaded by calibre from https://www.sciencenews.org/article/metabolism-disruption-intestinal-malrotation-frogs


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